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Ileocolitis - An Insight

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Ileocolitis is inflammation of the large and lower small intestines, a prevalent ailment associated with Crohn's disease.

Written by

Dr. Palak Jain

Medically reviewed by

Dr. Jagdish Singh

Published At May 22, 2024
Reviewed AtJune 10, 2024

Introduction

Abdominal pain is one of the symptoms of ileocolitis, which is brought on by inflammation or irritation of the ileum. The small intestine ends with the ileum, which marks the beginning of the large intestine. A prevalent ailment associated with Crohn's disease and other inflammatory bowel disorders (IBDs) is ileocolitis. If left untreated, ileocolitis can harm the digestive tract, necessitating surgery to repair or remove the affected tissue.

What Is Crohn's Disease?

Crohn's disease is a long-term autoimmune disorder that mostly affects the small and large intestines (colon), causing inflammation and irritation in the digestive tract. The two most prevalent types of inflammatory bowel disease are ulcerative colitis and Crohn's disease (IBD).

Symptoms of Crohn's disease can be unpleasant; diarrhea, cramping in the stomach, and discomfort in the abdomen are the most typical ones.

What Is Ileocolitis?

The most prevalent kind of Crohn's disease is ileocolitis. It produces inflammation in the colon (large intestine) and the ileum, the end of the small intestine, typically on the right side. Ileocolitis is identified in about half of patients with Crohn's disease. It belongs to a category of illnesses known as inflammatory bowel disease (IBD) and is a chronic, lifelong condition for which there is no known cure.

What Causes Ileocolitis?

Ileocolitis and other forms of Crohn's disease have an unclear underlying cause. Nonetheless, medical specialists think that a few factors might be involved.

They consist of:

  • Autoimmune Reaction: When the body's immune system unintentionally targets healthy cells, it can result in inflammation and eventually lead to Crohn's disease.

  • Family History: A person may be more susceptible to symptoms if they have a parent or sibling in their immediate family who has Crohn's disease.

  • Smoking: Smoking increases the chance of getting Crohn's disease by double.

  • Certain Drugs: Certain drugs, such as antibiotics, birth control tablets, and NSAIDs (nonsteroidal anti-inflammatory drugs), such as Ibuprofen or Aspirin, may marginally increase the chance of Crohn's disease.

  • Diet: Eating a lot of fat may also marginally raise the risk of developing Crohn's disease.

  • Genetics: If a close relative suffers from Crohn's disease, genetics may influence an individual's susceptibility to acquiring diseases such as ileocolitis by influencing the way the body reacts to specific IBD triggers.

  • Foods: High-fiber foods and carbonated beverages that might cause flare-ups of ileocolitis raise the chance of developing Crohn's disease. Significant evidence links high-fat diets to Crohn's disease. Foods and beverages that cause symptoms to flare up vary slightly from person to person.

What Are the Symptoms of Ileocolitis?

Ileocolitis symptoms might not be apparent at first if the inflamed area is small or the affected person is not eating anything, which could cause a flare-up. Ileocolitis's most typical symptoms include:

  • Abdominal pain and cramps in the lower or middle abdomen.

  • Diarrhea.

  • Weight loss without apparent cause.

Ileocolitis has symptoms similar to other bowel disorders, such as ileitis and jejunoileitis, that affect the colon and small intestine. To determine the most effective course of treatment, a medical practitioner will perform diagnostic testing to detect inflammation in the colon and ileum.

How to Diagnose Ileocolitis?

A medical expert will perform a physical examination and ask about the patient's medical history to better understand the patient's general health. These procedures can also illuminate the possible causes of ileocolitis or Crohn's disease, including nutrition, lifestyle, and other factors. A medical practitioner may also request diagnostic testing for additional symptom sources, such as infections.

Tests may consist of:

  • Blood tests to check for immune cell overproduction.

  • Stool samples should be taken to check for intestinal irritation indicators or pathogenic microorganisms.

To determine the causes of symptoms, a medical expert may request imaging studies to examine the digestive system. Imaging examinations consist of:

  • Endoscopy: To examine the intestines and seek out damaged or inflammatory sections.

  • X-Rays: To see the digestive system in more detail and to check for abnormalities.

  • CT Scans: To provide finely detailed, "sliced" pictures of the gastrointestinal system.

What Are the Treatment Modalities Used to Treat Ileocolitis?

The course of treatment for ileocolitis may vary depending on the underlying cause and severity of the symptoms. Currently, neither Crohn's disease nor ileocolitis can be cured completely.

The following are a few methods for treating ileocolitis:

1. In the long run, anti-inflammatory drugs such as corticosteroids and oral 5-aminosalicylates (5-ASAs) can help lessen symptoms and lower the chance of intestinal damage. Biologics and immune system suppressants, such as Infliximab, can also help prevent the immune system from attacking healthy colon tissue.

2. Changing One’s Diet to Lessen or Eliminate Triggers: An elimination diet can pinpoint particular triggers that help minimize symptoms. Consider consulting with a dietitian or nutritionist if the symptoms are severe or persistent. They can help create a structured eating plan tailored to the individual triggers.

3. Short-Term Restriction of Food and Drink Intake: This is known as "bowel rest," it involves a person eating or drinking very little for a few days to rid their intestines of inflammation. Collaborating with a healthcare provider is crucial for the best advice. One may get intravenous (IV) fluids or simply sip water for bowel rest.

4. To Remove Sick or Damaged Tissue by Surgery: By excising portions of the ileum or colon that have been harmed over time by inflammation, significant discomfort can be lessened, and inflammation in adjacent digestive tract segments can be stopped. Only after less intrusive therapies have failed is surgery advised for Crohn's disease.

Conclusion

A painful condition that might come and go over time is ileocolitis. Ileocolitis can damage the intestines and necessitate surgery if it is not adequately managed or cured. It is crucial to see a doctor about being evaluated for ileocolitis or other Crohn's disease-related disorders if one experiences persistent or regular bowel pain. There is no treatment available for Crohn's disease. After a diagnosis, the patient will collaborate closely with the medical professional to treat the illness, control symptoms, and avoid consequences. Long-term health can be enhanced by treatment.

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Dr. Jagdish Singh
Dr. Jagdish Singh

Medical Gastroenterology

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crohn's diseaseinflammation
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