Ask a Doctor Online Now
The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.
Answered by
Medically reviewed by
Patient's Query
Hi doctor,
I am planning to get married. My father got married to his elder sister's daughter, and my younger brother had cerebral palsy at birth. My sister has a low IQ, but she is manageable. In my fiance's family, her paternal grandfather is married to his sister's daughter. They have a daughter who is deaf. So please let me know if I can go ahead with this marriage proposal and have normal children without any genetic abnormalities due to the family history.
Hello,
Welcome to icliniq.com.
Cerebral palsy and a low intelligence quotient in your siblings need in-depth analysis. Both of these problems happening to consanguineous parents cannot be taken as incidental or independent of each other. The deafness on your fiance's side needs genetic evaluation too. We will evaluate and fix the genetic etiology in those affected on both sides of your family. Based on the genetic diagnosis made, the recurrence risk for your offspring can be predicted. If recurrence is expected, we will guide you towards early diagnosis (testing the fetus during pregnancy) and other possible methods of preventing a baby from being born with an abnormality.
Kindly plan accordingly.
I hope this helps.
Regards.
Was this conversation helpful?
Same symptoms don't mean you have the same problem. Consult a doctor now!
Clinical Genetics
Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.
This website uses cookies to ensure you get the best experience on our website. iCliniq privacy policy